What are the symptoms of high and low uric acid?

Expert answer:

The symptoms in high uric acid (hyperuricemia) are mainly characterized by joint pain in the lower limbs, such as knees, ankles, heels and toes. However, pains can affect any joint, including the hands.

Without proper treatment, high uric acid can also cause kidney stones (kidney stone), dysfunction or kidney failure and gout, a disease characterized by inflammation of the joints, caused by the deposition of uric acid crystals.

Increased uric acid in the blood can also increase insulin resistance, increasing the risk of diabetes.

It is worth noting that 2/3 or more of people with high uric acid are asymptomatic (they do not have any symptoms) and do not develop any disease.

Already the low uric acid (hypouricemia) does not usually cause symptoms and is an uncommon condition. It is usually associated with certain liver or kidney diseases, exposure to toxic substances, use of certain medications or a hereditary metabolic problem.

If you have abnormal uric acid levels on your exams, or if you experience any of these symptoms, seek a family doctor or general practitioner for evaluation.