Myocytes high or low on leukogram, what does it mean?

Expert answer:

The presence of myelocytes in the leukogram may be a sign of infections or acute inflammation or yet cancer. In such cases, other immature white blood cells, such as myeloblasts, promyelocytes, metamielocytes, and rods may be present.

Myelocytes are white blood cells still in the process of maturation. These are neutrophils young, a type of defense cell that is part of the immune system.

When the number of myelocytes is high, it means that the bone marrow is having to produce more neutrophils than normal. Increased myelocytes are often accompanied by an increase in mature (segmented) neutrophils.

However, when the amount of young cells is greater than that of mature cells, it indicates that the body is ordering many neutrophils from the bone marrow where they are produced. Since there is no time for them to mature, they are released immature for circulation. This is common in inflammation and more serious infections.

The number of neutrophils may also be high in other conditions, such as bleeding and use of certain medicines.

On the other hand, when myelocytes are low, it may indicate defects in the production of cells or be a sign of increased use and destruction of these white blood cells.

This can happen in many situations, such as stress, genetic problems, diseases, use of medications, infections, treatment with chemo, among other causes.

People with low myelocyte stores have a higher risk of developing fungal and bacterial infections, as these cells protect the body against microorganisms and invading agents.

Remembering that the result of the leukogram, as well as the whole blood count, must be interpreted by the doctor who requested the examination according to the patient's history and clinical examination.

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